40Research opportunities
44Commercial whitespaces
39Ecosystem support needs
Key: Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based
Opportunity Production platform Value chain segment Technology sector End product focus Relevant actor
B2B growth factors for proliferation

There is a need for a supplier of low-cost growth factors produced without the use of animals to support the proliferation phase of cultivated meat production. The cost of growth…

Cultivated icon Cultivated Fermentation icon Fermentation Production R&D Raw Materials, Ingredients, & Inputs Bioprocess design Cell culture media Seafood-relevant Species-agnostic Academics Industry Startups
Affordable animal-free omega-3 ingredients for alternative seafood and other alternative protein applications

In order to appeal to health-conscious consumers, alternative seafood products should contain similar omega-3 fatty acids, especially DHA and EPA, content to conventional seafood. Animal-free omega-3 ingredients can be expensive…

Fermentation icon Fermentation Plant-based icon Plant-Based Investment Production R&D Raw Materials, Ingredients, & Inputs Bioprocess design Crop development Host strain development Ingredient optimization Target molecule selection Seafood Industry Investors Startups
Understanding uptake and interconversion of omega-3 fatty acids by cultivated fish cells

Although fish are one of the best dietary sources of long-chain omega-3 fatty acids (FAs), these compounds are mostly bioaccumulated from a fish’s diet rather than synthesized de novo. Consistent…

Cultivated icon Cultivated R&D Raw Materials, Ingredients, & Inputs Cell culture media Cell line development Host strain development Seafood Seafood-relevant Academics Industry Startups
Scaffolding development for culinary and biomechanical requirements of cultivated seafood

A number of published studies have focused on scaffolds for cultivated meat (see Related Efforts) yet, to our knowledge, no studies have specifically attempted to formulate scaffolds for fish or…

Cultivated icon Cultivated R&D Raw Materials, Ingredients, & Inputs Cell line development Scaffolding Seafood Seafood-relevant Academics Industry Startups
Production process innovations for fiber formation and improved plant protein texturization

Fibers from techniques like electrospinning, jet spinning, or blow spinning may be able to impart a desirable texture to a given product.

Plant-based icon Plant-Based End Products Production R&D End product formulation & manufacturing Seafood-relevant Academics Industry Startups
Coordination among investors with alternative protein industry-specific expertise

Investors specializing in alternative proteins should be leveraged to educate the broader investment community through coalitions, syndicated deals, and co-investments with industry-agnostic investors, and spearhead efforts to facilitate later-stage funding…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based Investment Species-agnostic GFI Investors Startups
“Rainbow roll 2.0” as a showcase product for cultivated seafood

Thin sheets of cultivated fish for layering on the outside of maki rolls and other sushi products could be an attractive market-entry commercial product. Producing thin sheets of tissue is…

Cultivated icon Cultivated End Products End product formulation & manufacturing Seafood Startups
Microbial strain-development contract research organizations for alternative protein applications

While emerging fermentation-derived ingredient companies often optimize their strain’s productivity in-house, it may be more efficacious for startups to engage contract research organizations with both deep microbial strain development expertise…

Fermentation icon Fermentation R&D Host strain development Species-agnostic Industry Startups
Guaranteed offtake contracts for products and ingredients

Guaranteed offtake agreements, where buyers commit to purchase a volume of product, can help secure loans for infrastructure and other high-cost projects.

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based End Products Investment Production End product formulation & manufacturing Species-agnostic Industry Policymakers
Expanding private label plant-based offerings

Brands, dedicated private labelers, and co-manufacturers can take advantage of the private labeling opportunity, and would benefit from developing a wide range of products to fit every category and access…

Fermentation icon Fermentation Plant-based icon Plant-Based Business Services Distribution Channels End Products Production End product formulation & manufacturing Species-agnostic Industry

Get involved

If you’d like to fund a research project, work on any of these solutions, share information about related efforts that are already underway, or elevate new ideas for advancing the alternative protein industry, we’d love to hear from you!

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Explore key innovation priorities

Review commercial whitespaces, research gaps, technological needs, and investment priorities at each stage of the alternative protein value chain.

How we built this

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Executive summary

Get an overview of GFI’s Solutions initiative and a summary of key resources.

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Full report

Delve into the full report on the motivation, methodology, rationale, and key findings and recommendations of the Solutions initiative.

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Futures wheels analysis

Explore our framework for uncovering second-order or third-order consequences and implications of hypothetical future scenarios to support better decision-making in the present.

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Future-proofing

Discover key findings from GFI’s premortem analysis of potential threats to the widespread adoption of alternative proteins, including strategies to avoid or mitigate the most pressing risks.