45+Research opportunities
50+Commercial whitespaces
35+Ecosystem support needs

Additional Filters


Key: Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based
Opportunity Production platform Value chain segment Technology sector End product focus Relevant actor Maturity level Solution category Topic
High-performance oxygen carriers for cultivated meat

Mammalian cell culture performance can be limited by oxygen and carbon dioxide levels or by shear stress associated with sparging and mixing. The use of protein-based oxygen carriers could help…

Cultivated icon Cultivated R&D Bioprocess design Cell culture media Species-agnostic Academics Startups Commercial Research Science
Consumer and sensory research to guide alternative fish R&D

Consumer and sensory research can help companies and academic researchers better understand seafood consumers’ needs and desires. Understanding consumers’ needs will allow alternative fish researchers to ask and prioritize the…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based End Products End product formulation & manufacturing Seafood Academics Industry Startups Commercial Research Science
Catalog of animal meat flavors

Creating a catalog of molecules responsible for the characteristic flavor of a species will enable alternative protein product manufacturers to create products that more accurately replicate the sensory experience of…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based End Products Production R&D Raw Materials, Ingredients, & Inputs Crop development End product formulation & manufacturing Ingredient optimization Target molecule selection Seafood-relevant Academics GFI Industry NGO’s Startups Commercial Ecosystem Research Industry Science
Developing scalable, fit-for-purpose bioreactor and bioprocessing technologies for cultivated meat

Optimizing bioreactor and bioprocessing technologies for the needs of the cultivated meat industry has the potential to substantially reduce the cost of cultivated meat production. Innovations in cultivated meat bioprocessing…

Cultivated icon Cultivated Production R&D Bioprocess design Species-agnostic Academics Industry Startups Commercial Research Science
Cultivated, fermentation-derived, or hybrid surimi

There has been little publicly announced R&D and commercial effort to develop cultivated, fermentation-derived, or hybrid surimi. Compared to other meat products, surimi is likely to be by far one…

Cultivated icon Cultivated Fermentation icon Fermentation End Products End product formulation & manufacturing Target molecule selection Seafood Industry Investors Startups Commercial Research Science
Optimizing fat profiles for nutritional and sensory properties

Because alternative meat’s fat content and fatty acid profile can be more easily controlled than conventional meat’s, there is an opportunity to alter fat content for nutritional benefits. Additional research…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based End Products Production R&D Cell culture media End product formulation & manufacturing Target molecule selection Seafood-relevant Academics Industry Startups Commercial Research Science
Mapping animal cell metabolism to optimize media formulation

The cost and environmental impact of cultivated meat are driven by the cell culture media formulation and its conversion efficiency into meat. Metabolic modeling and engineering techniques can aid media…

Cultivated icon Cultivated Production R&D Raw Materials, Ingredients, & Inputs Cell culture media Cell line development Species-agnostic Academics Industry Startups Commercial Research
Incorporating growth factors into scaffolds to reduce costs and introduce spatial heterogeneity

Growth factors (GFs) can be incorporated into scaffolds as a strategy for both reducing costs and improving product quality of cultivated meat. Open-access research is needed to test the feasibility…

Cultivated icon Cultivated End Products Production R&D Scaffolding Seafood-relevant Academics Industry Startups Commercial Research
Scaffolds and structural approaches to optimize fat distribution and content in cultivated meat

The inclusion of fat and marbling in cultivated meat is likely to increase its flavor, texture, and consumer appeal. Structural approaches using edible microcarriers, hydrogels, and 3D bioprinting present promising…

Cultivated icon Cultivated End Products Production R&D Raw Materials, Ingredients, & Inputs Bioprocess design End product formulation & manufacturing Scaffolding Species-agnostic Academics Industry Startups Commercial Research Industry Science
Hybrid products to optimize nutrition, taste, cost, and sustainability

Hybrid products are a promising means to improve the cost and sustainability of animal-derived meat while improving the taste of plant proteins. Promoting the health benefits of hybrids may facilitate…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based Demand Generation End Products Production R&D Raw Materials, Ingredients, & Inputs End product formulation & manufacturing Ingredient optimization Species-agnostic Academics Industry Investors Startups Commercial Industry Science

Get involved

If you’d like to fund a research project, work on any of these solutions, share information about related efforts that are already underway, or elevate new ideas for advancing the alternative protein industry, we’d love to hear from you!

Swinging lit lightbulb graphic representing gfi's innovation priorities

Explore key innovation priorities

Review commercial whitespaces, research gaps, technological needs, and investment priorities at each stage of the alternative protein value chain.

How we built this

Advancing solutions for alternative proteins executive summary icon

Executive summary

Get an overview of GFI’s Solutions initiative and a summary of key resources.

Advancing solutions for alternative proteins full report icon

Full report

Delve into the full report on the motivation, methodology, rationale, and key findings and recommendations of the Solutions initiative.

Advancing solutions for alternative proteins future wheels analysis icon

Futures wheels analysis

Explore our framework for uncovering second-order or third-order consequences and implications of hypothetical future scenarios to support better decision-making in the present.

Advancing solutions for alternative proteins future-proofing report icon

Future-proofing

Discover key findings from GFI’s premortem analysis of potential threats to the widespread adoption of alternative proteins, including strategies to avoid or mitigate the most pressing risks.