45+Research opportunities
50+Commercial whitespaces
35+Ecosystem support needs

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Key: Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based
Opportunity Production platform Value chain segment Technology sector End product focus Relevant actor Maturity level Solution category Topic
High-performance oxygen carriers for cultivated meat

Mammalian cell culture performance can be limited by oxygen and carbon dioxide levels or by shear stress associated with sparging and mixing. The use of protein-based oxygen carriers could help…

Cultivated icon Cultivated R&D Bioprocess design Cell culture media Species-agnostic Academics Startups Commercial Research Science
Directed evolution using Raman activated cell sorting

The combination of flow cytometry—which allows single cell analysis and sorting—with Raman spectroscopy—which allows crude biochemical analysis of cells—can be used to develop new strains of microorganisms with enriched protein,…

Fermentation icon Fermentation R&D Host strain development Species-agnostic Academics Industry Startups Research Science
Developing scalable, fit-for-purpose bioreactor and bioprocessing technologies for cultivated meat

Optimizing bioreactor and bioprocessing technologies for the needs of the cultivated meat industry has the potential to substantially reduce the cost of cultivated meat production. Innovations in cultivated meat bioprocessing…

Cultivated icon Cultivated Production R&D Bioprocess design Species-agnostic Academics Industry Startups Commercial Research Science
Mapping animal cell metabolism to optimize media formulation

The cost and environmental impact of cultivated meat are driven by the cell culture media formulation and its conversion efficiency into meat. Metabolic modeling and engineering techniques can aid media…

Cultivated icon Cultivated Production R&D Raw Materials, Ingredients, & Inputs Cell culture media Cell line development Species-agnostic Academics Industry Startups Commercial Research
Consumer education on the food safety of cultivated meat

Consumer education on the food safety of cultivated meat can positively impact consumer acceptance when sufficient information is provided. Additional research and efforts to increase transparent science communication on the…

Cultivated icon Cultivated Fermentation icon Fermentation Demand Generation End Products Species-agnostic Academics GFI Industry NGO’s Startups Ecosystem Science
Ensuring appropriate food safety controls for cultivated meat

Sterilization guidelines from well-established biomedical and food industries can act as helpful templates for safe cultivated meat production. However, more research is needed to identify potentially novel production hazards for…

Cultivated icon Cultivated Compliance Species-agnostic Ecosystem Policy Research Policy
Scaffolds and structural approaches to optimize fat distribution and content in cultivated meat

The inclusion of fat and marbling in cultivated meat is likely to increase its flavor, texture, and consumer appeal. Structural approaches using edible microcarriers, hydrogels, and 3D bioprinting present promising…

Cultivated icon Cultivated End Products Production R&D Raw Materials, Ingredients, & Inputs Bioprocess design End product formulation & manufacturing Scaffolding Species-agnostic Academics Industry Startups Commercial Research Industry Science
Hybrid products to optimize nutrition, taste, cost, and sustainability

Hybrid products are a promising means to improve the cost and sustainability of animal-derived meat while improving the taste of plant proteins. Promoting the health benefits of hybrids may facilitate…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based Demand Generation End Products Production R&D Raw Materials, Ingredients, & Inputs End product formulation & manufacturing Ingredient optimization Species-agnostic Academics Industry Investors Startups Commercial Industry Science
Cost-effective sterility controls for cultivated meat

Meticulous attention to sterility controls throughout cultivated meat production is essential to optimize food safety, but the cost of biopharmaceutical-based sterility—the current standard for cell-based processes—is incongruent with large-scale food…

Cultivated icon Cultivated Production Bioprocess design Cell culture media End product formulation & manufacturing Species-agnostic Industry Policymakers Startups Ecosystem Research Industry Policy Science
Scientist / engineer outreach and education

To expand the technical talent pipeline, various players in the alternative protein field should reach out to scientists and engineers in relevant disciplines (e.g., biotech, biopharma, and food science) to…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based Workforce Species-agnostic Academics Donors GFI Industry NGO’s Policymakers Startups Ecosystem

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If you’d like to fund a research project, work on any of these solutions, share information about related efforts that are already underway, or elevate new ideas for advancing the alternative protein industry, we’d love to hear from you!

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Explore key innovation priorities

Review commercial whitespaces, research gaps, technological needs, and investment priorities at each stage of the alternative protein value chain.

How we built this

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Executive summary

Get an overview of GFI’s Solutions initiative and a summary of key resources.

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Full report

Delve into the full report on the motivation, methodology, rationale, and key findings and recommendations of the Solutions initiative.

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Futures wheels analysis

Explore our framework for uncovering second-order or third-order consequences and implications of hypothetical future scenarios to support better decision-making in the present.

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Future-proofing

Discover key findings from GFI’s premortem analysis of potential threats to the widespread adoption of alternative proteins, including strategies to avoid or mitigate the most pressing risks.