40Research opportunities
44Commercial whitespaces
39Ecosystem support needs
Key: Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based
Opportunity Production platform Value chain segment Technology sector End product focus Relevant actor
B2B growth factors for proliferation

There is a need for a supplier of low-cost growth factors produced without the use of animals to support the proliferation phase of cultivated meat production. The cost of growth…

Cultivated icon Cultivated Fermentation icon Fermentation Production R&D Raw Materials, Ingredients, & Inputs Bioprocess design Cell culture media Seafood-relevant Species-agnostic Academics Industry Startups
Affordable animal-free omega-3 ingredients for alternative seafood and other alternative protein applications

In order to appeal to health-conscious consumers, alternative seafood products should contain similar omega-3 fatty acids, especially DHA and EPA, content to conventional seafood. Animal-free omega-3 ingredients can be expensive…

Fermentation icon Fermentation Plant-based icon Plant-Based Investment Production R&D Raw Materials, Ingredients, & Inputs Bioprocess design Crop development Host strain development Ingredient optimization Target molecule selection Seafood Industry Investors Startups
Novel methods for long-chain omega-3 fatty acid production

As the alternative seafood industry scales up, a low-cost and abundant source of long-chain omega-3 polyunsaturated fatty acids will become necessary. Several means of producing these compounds have been investigated…

Fermentation icon Fermentation R&D Raw Materials, Ingredients, & Inputs Bioprocess design Host strain development Ingredient optimization Target molecule selection Seafood Academics Industry Startups
Preventing oxidation of omega-3 fatty acids before and after addition to alternative seafood products

Deeper fundamental knowledge of the causes and prevention of oxidation of omega-3 fatty acids before, during, and after addition to alternative seafood products is needed to improve their nutritional and…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based End Products Investment Production R&D Raw Materials, Ingredients, & Inputs Bioprocess design Crop development End product formulation & manufacturing Host strain development Ingredient optimization Target molecule selection Seafood Academics Industry Investors Startups
Understanding uptake and interconversion of omega-3 fatty acids by cultivated fish cells

Although fish are one of the best dietary sources of long-chain omega-3 fatty acids (FAs), these compounds are mostly bioaccumulated from a fish’s diet rather than synthesized de novo. Consistent…

Cultivated icon Cultivated R&D Raw Materials, Ingredients, & Inputs Cell culture media Cell line development Host strain development Seafood Seafood-relevant Academics Industry Startups
Scaffolding development for culinary and biomechanical requirements of cultivated seafood

A number of published studies have focused on scaffolds for cultivated meat (see Related Efforts) yet, to our knowledge, no studies have specifically attempted to formulate scaffolds for fish or…

Cultivated icon Cultivated R&D Raw Materials, Ingredients, & Inputs Cell line development Scaffolding Seafood Seafood-relevant Academics Industry Startups
Building interdisciplinary university research centers of excellence

Interdisciplinary research is essential for tackling many of the complex problems facing today’s world. Though the number of research projects advancing alternative protein science has increased in recent years, this…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based R&D Workforce Species-agnostic Academics Donors Industry NGO’s Policymakers Startups
Production process innovations for fiber formation and improved plant protein texturization

Fibers from techniques like electrospinning, jet spinning, or blow spinning may be able to impart a desirable texture to a given product.

Plant-based icon Plant-Based End Products Production R&D End product formulation & manufacturing Seafood-relevant Academics Industry Startups
Coordination among investors with alternative protein industry-specific expertise

Investors specializing in alternative proteins should be leveraged to educate the broader investment community through coalitions, syndicated deals, and co-investments with industry-agnostic investors, and spearhead efforts to facilitate later-stage funding…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based Investment Species-agnostic GFI Investors Startups
Improving efficiency and assessment of adaptation to suspension growth

Improving methods for adapting cells to suspension culture can facilitate cell line development and bioprocess design for cultivated meat.

Cultivated icon Cultivated R&D Bioprocess design Cell line development Seafood-relevant Academics Industry Startups

Get involved

If you’d like to fund a research project, work on any of these solutions, share information about related efforts that are already underway, or elevate new ideas for advancing the alternative protein industry, we’d love to hear from you!

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Explore key innovation priorities

Review commercial whitespaces, research gaps, technological needs, and investment priorities at each stage of the alternative protein value chain.

How we built this

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Executive summary

Get an overview of GFI’s Solutions initiative and a summary of key resources.

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Full report

Delve into the full report on the motivation, methodology, rationale, and key findings and recommendations of the Solutions initiative.

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Futures wheels analysis

Explore our framework for uncovering second-order or third-order consequences and implications of hypothetical future scenarios to support better decision-making in the present.

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Future-proofing

Discover key findings from GFI’s premortem analysis of potential threats to the widespread adoption of alternative proteins, including strategies to avoid or mitigate the most pressing risks.