40Research opportunities
44Commercial whitespaces
39Ecosystem support needs
Key: Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based
Opportunity Production platform Value chain segment Technology sector End product focus Relevant actor
B2B growth factors for proliferation

There is a need for a supplier of low-cost growth factors produced without the use of animals to support the proliferation phase of cultivated meat production. The cost of growth…

Cultivated icon Cultivated Fermentation icon Fermentation Production R&D Raw Materials, Ingredients, & Inputs Bioprocess design Cell culture media Seafood-relevant Species-agnostic Academics Industry Startups
Understanding uptake and interconversion of omega-3 fatty acids by cultivated fish cells

Although fish are one of the best dietary sources of long-chain omega-3 fatty acids (FAs), these compounds are mostly bioaccumulated from a fish’s diet rather than synthesized de novo. Consistent…

Cultivated icon Cultivated R&D Raw Materials, Ingredients, & Inputs Cell culture media Cell line development Host strain development Seafood Seafood-relevant Academics Industry Startups
Forging product development partnerships among ingredient suppliers and manufacturers

Opportunities exist to coordinate product development partnerships between ingredient suppliers, strategic partners, and product manufacturers to directly engage more holistically on product formulation.

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based End Products Production Raw Materials, Ingredients, & Inputs Cell culture media Crop development Feedstocks Ingredient optimization Scaffolding Species-agnostic GFI Industry
Species-specific research toolkits for cultivated meat-relevant species

Coordinated efforts to develop standardized, comprehensive research toolkits of meat-relevant species would exponentially accelerate cultivated meat research.

Cultivated icon Cultivated Compliance R&D Cell culture media Cell line development End product formulation & manufacturing Seafood-relevant Academics GFI Industry NGO’s Startups
Systematic investigation of growth factor needs and effects

Open-access research into growth factors required for proliferation, maintenance, and differentiation of cell types relevant to cultivated meat will support both academic and industry research efforts. This research could include…

Cultivated icon Cultivated Fermentation icon Fermentation R&D Raw Materials, Ingredients, & Inputs Cell culture media Target molecule selection Seafood-relevant Academics
Growth factors from conditioned cell culture media

Rather than relying on recombinant growth factors, cultivated meat companies could use conditioned media from animal cells producing high levels of these molecules.

Cultivated icon Cultivated Fermentation icon Fermentation R&D Raw Materials, Ingredients, & Inputs Cell culture media Target molecule selection Seafood-relevant Academics Industry Startups
Post-harvest processes and end product characterization for cultivated meat

A number of cellular processes occurring after slaughter are known to affect the quality and sensory properties of conventional meat. Cultivated meat will offer unprecedented control over these parameters and…

Cultivated icon Cultivated End Products R&D Bioprocess design Cell culture media End product formulation & manufacturing Seafood-relevant Academics Startups
Pooled procurement/group purchasing for ingredients and inputs

Many alternative protein companies use similar inputs, but individually lack the purchasing power to negotiate favorable contract terms. A pooled procurement/group purchasing mechanism for ingredients, inputs (growth factors, media, etc.),…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based Business Services Raw Materials, Ingredients, & Inputs Cell culture media Crop development Feedstocks Species-agnostic Industry NGO’s Startups
Cultivated meat co-product valorization

Animal cell metabolism within cultivators can produce useful co-product side streams that provide monetary value to the manufacturer while creating a novel source of inputs for other industries. Potential side…

Cultivated icon Cultivated R&D Raw Materials, Ingredients, & Inputs Bioprocess design Cell culture media Seafood-relevant Academics Industry Startups
Open-access formulations & optimization methods for cell culture media and growth factor cocktails

The availability of more open-access formulations will provide a foundation to enable both academic researchers and startup companies to develop their own customized formulations with far less effort and cost.

Cultivated icon Cultivated R&D Raw Materials, Ingredients, & Inputs Cell culture media Seafood-relevant Academics

Get involved

If you’d like to fund a research project, work on any of these solutions, share information about related efforts that are already underway, or elevate new ideas for advancing the alternative protein industry, we’d love to hear from you!

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Explore key innovation priorities

Review commercial whitespaces, research gaps, technological needs, and investment priorities at each stage of the alternative protein value chain.

How we built this

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Executive summary

Get an overview of GFI’s Solutions initiative and a summary of key resources.

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Full report

Delve into the full report on the motivation, methodology, rationale, and key findings and recommendations of the Solutions initiative.

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Futures wheels analysis

Explore our framework for uncovering second-order or third-order consequences and implications of hypothetical future scenarios to support better decision-making in the present.

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Future-proofing

Discover key findings from GFI’s premortem analysis of potential threats to the widespread adoption of alternative proteins, including strategies to avoid or mitigate the most pressing risks.