45+Research opportunities
50+Commercial whitespaces
35+Ecosystem support needs

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Key: Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based
Opportunity Production platform Value chain segment Technology sector End product focus Relevant actor Maturity level Solution category Topic
Consumer education on the food safety of cultivated meat

Consumer education on the food safety of cultivated meat can positively impact consumer acceptance when sufficient information is provided. Additional research and efforts to increase transparent science communication on the…

Cultivated icon Cultivated Fermentation icon Fermentation Demand Generation End Products Species-agnostic Academics GFI Industry NGO’s Startups Ecosystem Science
Incorporating growth factors into scaffolds to reduce costs and introduce spatial heterogeneity

Growth factors (GFs) can be incorporated into scaffolds as a strategy for both reducing costs and improving product quality of cultivated meat. Open-access research is needed to test the feasibility…

Cultivated icon Cultivated End Products Production R&D Scaffolding Seafood-relevant Academics Industry Startups Commercial Research
Scaffolds and structural approaches to optimize fat distribution and content in cultivated meat

The inclusion of fat and marbling in cultivated meat is likely to increase its flavor, texture, and consumer appeal. Structural approaches using edible microcarriers, hydrogels, and 3D bioprinting present promising…

Cultivated icon Cultivated End Products Production R&D Raw Materials, Ingredients, & Inputs Bioprocess design End product formulation & manufacturing Scaffolding Species-agnostic Academics Industry Startups Commercial Research Industry Science
Promoting stemness and proliferation in fish cell cultures

Efficient and cost-effective cultivated fish production will require precise optimization to encourage fast proliferation and highly efficient use of inputs while preventing premature differentiation. A variety of strategies can be…

Cultivated icon Cultivated Production R&D Cell culture media Cell line development Seafood Academics Industry Startups Research Science
Hybrid products to optimize nutrition, taste, cost, and sustainability

Hybrid products are a promising means to improve the cost and sustainability of animal-derived meat while improving the taste of plant proteins. Promoting the health benefits of hybrids may facilitate…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based Demand Generation End Products Production R&D Raw Materials, Ingredients, & Inputs End product formulation & manufacturing Ingredient optimization Species-agnostic Academics Industry Investors Startups Commercial Industry Science
Scientist / engineer outreach and education

To expand the technical talent pipeline, various players in the alternative protein field should reach out to scientists and engineers in relevant disciplines (e.g., biotech, biopharma, and food science) to…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based Workforce Species-agnostic Academics Donors GFI Industry NGO’s Policymakers Startups Ecosystem
Life Cycle Assessment for alternative seafood relative to conventional fishing and aquaculture

To date, no robust environmental assessments have been conducted to compare alternative seafood to its conventional counterparts. An open-access, quantitative analysis of the relative environmental impacts of alternative seafood will…

Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based Demand Generation Distribution Channels End Products Investment Production R&D Raw Materials, Ingredients, & Inputs Seafood Academics GFI Industry Research Science
Plant-based scaffolds to improve cultivated meat nutrition

A variety of plant-based scaffolds present the opportunity to combine the natural nutritional and structural benefits of plants with the taste and high protein of cultivated meat. Bacterial nanocellulose from…

Cultivated icon Cultivated Plant-based icon Plant-Based End Products Investment Production R&D Raw Materials, Ingredients, & Inputs Bioprocess design End product formulation & manufacturing Scaffolding Species-agnostic Academics Industry Startups Commercial Research Industry Science
Animal-free, non-recombinant albumin and transferrin for cultivated meat

The identification of non-animal, non-recombinant proteins with similar functionality to serum albumin and transferrin will lead to major cost reductions in cell culture media development, facilitating progress toward achieving price…

Cultivated icon Cultivated Plant-based icon Plant-Based Production R&D Raw Materials, Ingredients, & Inputs Cell culture media Crop development Target molecule selection Species-agnostic Academics Industry Investors Startups Commercial Research Industry Science
Semi-continuous bioprocess for whole cut cultivated meat using simultaneous perfusion and stretch

Stretching of engineered muscle constructs has been previously demonstrated to induce alignment and maturation of muscle fibers, which is desirable for whole cut cultivated meat. Stretch stimuli could also be…

Cultivated icon Cultivated Production R&D Bioprocess design Scaffolding Terrestrial-specific Academics Industry Startups Commercial Research Industry Science

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If you’d like to fund a research project, work on any of these solutions, share information about related efforts that are already underway, or elevate new ideas for advancing the alternative protein industry, we’d love to hear from you!

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Explore key innovation priorities

Review commercial whitespaces, research gaps, technological needs, and investment priorities at each stage of the alternative protein value chain.

How we built this

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Executive summary

Get an overview of GFI’s Solutions initiative and a summary of key resources.

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Full report

Delve into the full report on the motivation, methodology, rationale, and key findings and recommendations of the Solutions initiative.

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Futures wheels analysis

Explore our framework for uncovering second-order or third-order consequences and implications of hypothetical future scenarios to support better decision-making in the present.

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Future-proofing

Discover key findings from GFI’s premortem analysis of potential threats to the widespread adoption of alternative proteins, including strategies to avoid or mitigate the most pressing risks.