Alternative Protein Solutions Database
Discover ideas for new startups, commercial ventures and products, research projects, ecosystem support, and investment opportunities for plant-based, cultivated, and fermentation-derived proteins.
|Opportunity||Production platform||Value chain segment||Technology sector||End product focus||Relevant actor||Maturity level||Solution category||Topic|
Ensuring appropriate food safety controls for cultivated meat
Sterilization guidelines from well-established biomedical and food industries can act as helpful templates for safe cultivated meat production. However, more research is needed to identify potentially novel production hazards for…
|Cultivated||Compliance||Species-agnostic||Ecosystem Policy Research||Policy|
Incorporating growth factors into scaffolds to reduce costs and introduce spatial heterogeneity
Growth factors (GFs) can be incorporated into scaffolds as a strategy for both reducing costs and improving product quality of cultivated meat. Open-access research is needed to test the feasibility…
|Cultivated||End Products Production R&D||Scaffolding||Seafood-relevant||Academics Industry Startups||Commercial Research|
Scaffolds and structural approaches to optimize fat distribution and content in cultivated meat
The inclusion of fat and marbling in cultivated meat is likely to increase its flavor, texture, and consumer appeal. Structural approaches using edible microcarriers, hydrogels, and 3D bioprinting present promising…
|Cultivated||End Products Production R&D Raw Materials, Ingredients, & Inputs||Bioprocess design End product formulation & manufacturing Scaffolding||Species-agnostic||Academics Industry Startups||Commercial Research||Industry Science|
Promoting stemness and proliferation in fish cell cultures
Efficient and cost-effective cultivated fish production will require precise optimization to encourage fast proliferation and highly efficient use of inputs while preventing premature differentiation. A variety of strategies can be…
|Cultivated||Production R&D||Cell culture media Cell line development||Seafood||Academics Industry Startups||Research||Science|
Cost-effective sterility controls for cultivated meat
Meticulous attention to sterility controls throughout cultivated meat production is essential to optimize food safety, but the cost of biopharmaceutical-based sterility—the current standard for cell-based processes—is incongruent with large-scale food…
|Cultivated||Production||Bioprocess design Cell culture media End product formulation & manufacturing||Species-agnostic||Industry Policymakers Startups||Ecosystem Research||Industry Policy Science|
B2B media development company
The cultivated meat industry needs dedicated suppliers of low-cost, food-grade cell culture media to reduce cultivated meat production costs. Close collaboration between the customer and supplier will be required in…
|Cultivated||R&D Raw Materials, Ingredients, & Inputs||Cell culture media||Seafood-relevant||Industry Investors Startups||Commercial Research|
Life Cycle Assessment for alternative seafood relative to conventional fishing and aquaculture
To date, no robust environmental assessments have been conducted to compare alternative seafood to its conventional counterparts. An open-access, quantitative analysis of the relative environmental impacts of alternative seafood will…
|Cultivated Fermentation Plant-Based||Demand Generation Distribution Channels End Products Investment Production R&D Raw Materials, Ingredients, & Inputs||Seafood||Academics GFI Industry||Research||Science|
Plant-based scaffolds to improve cultivated meat nutrition
A variety of plant-based scaffolds present the opportunity to combine the natural nutritional and structural benefits of plants with the taste and high protein of cultivated meat. Bacterial nanocellulose from…
|Cultivated Plant-Based||End Products Investment Production R&D Raw Materials, Ingredients, & Inputs||Bioprocess design End product formulation & manufacturing Scaffolding||Species-agnostic||Academics Industry Startups||Commercial Research||Industry Science|
Animal-free, non-recombinant albumin and transferrin for cultivated meat
The identification of non-animal, non-recombinant proteins with similar functionality to serum albumin and transferrin will lead to major cost reductions in cell culture media development, facilitating progress toward achieving price…
|Cultivated Plant-Based||Production R&D Raw Materials, Ingredients, & Inputs||Cell culture media Crop development Target molecule selection||Species-agnostic||Academics Industry Investors Startups||Commercial Research||Industry Science|
Semi-continuous bioprocess for whole cut cultivated meat using simultaneous perfusion and stretch
Stretching of engineered muscle constructs has been previously demonstrated to induce alignment and maturation of muscle fibers, which is desirable for whole cut cultivated meat. Stretch stimuli could also be…
|Cultivated||Production R&D||Bioprocess design Scaffolding||Terrestrial-specific||Academics Industry Startups||Commercial Research||Industry Science|
If you’d like to fund a research project, work on any of these solutions, share information about related efforts that are already underway, or elevate new ideas for advancing the alternative protein industry, we’d love to hear from you!
Explore key innovation priorities
Review commercial whitespaces, research gaps, technological needs, and investment priorities at each stage of the alternative protein value chain.
How we built this
Get an overview of GFI’s Solutions initiative and a summary of key resources.
Delve into the full report on the motivation, methodology, rationale, and key findings and recommendations of the Solutions initiative.
Futures wheels analysis
Explore our framework for uncovering second-order or third-order consequences and implications of hypothetical future scenarios to support better decision-making in the present.
Discover key findings from GFI’s premortem analysis of potential threats to the widespread adoption of alternative proteins, including strategies to avoid or mitigate the most pressing risks.