40Research opportunities
44Commercial whitespaces
39Ecosystem support needs
Key: Icon cultivated Cultivated Icon fermentation Fermentation Icon plant based Plant-Based
Opportunity Production platform Solution category Value chain segment Technology sector Maturity level
Production process innovations for fiber formation and improved plant protein texturization

Fibers from techniques like electrospinning, jet spinning, or blow spinning may be able to impart a desirable texture to a given product.

Icon plant based Plant-Based Commercial Research End Products Production R&D End product formulation & manufacturing 2 – Early adoption
Improving efficiency and assessment of adaptation to suspension growth

Improving methods for adapting cells to suspension culture can facilitate cell line development and bioprocess design for cultivated meat.

Icon cultivated Cultivated Research R&D Bioprocess design Cell line development 1 – Inception
Species-specific genomic studies enabling assay development for regulatory standards and cell line optimization

A suite of assays and genomic knowledge exists for humans and commonly used laboratory species such as mice or fruit flies. However, the same species-specific infrastructure does not exist equally…

Icon cultivated Cultivated Research R&D Cell line development
Guidelines for cultivated meat starter cell selection

Improving our understanding of the relative advantages and disadvantages of different cell types for cultivated meat would enable companies to make these decisions more effectively with less duplicative effort.

Icon cultivated Cultivated Research R&D Raw Materials, Ingredients, & Inputs Cell line development 1 – Inception
Mapping the secretome of animal myoblasts, adipocytes, and other cells used in cultivated meat

Stem cells secrete a variety of signaling factors that can influence the behavior of surrounding cells, known as paracrine signals. In high-density bioprocesses, these secreted factors can accumulate to concentrations…

Icon cultivated Cultivated Research Production R&D Cell line development
Microbial strain-development contract research organizations for alternative protein applications

While emerging fermentation-derived ingredient companies often optimize their strain’s productivity in-house, it may be more efficacious for startups to engage contract research organizations with both deep microbial strain development expertise…

Icon fermentation Fermentation Commercial Ecosystem Research R&D Host strain development
Plants as a recombinant protein expression platform for functional food ingredients

Crop plants used as recombinant protein production hosts could offer benefits of minimal processing, cheaper equipment, and fewer downstream purification costs.

Icon fermentation Fermentation Icon plant based Plant-Based Commercial Research Production R&D Raw Materials, Ingredients, & Inputs Crop development Ingredient optimization 2 – Early adoption
Species-specific research toolkits for cultivated meat-relevant species

Coordinated efforts to develop standardized, comprehensive research toolkits of meat-relevant species would exponentially accelerate cultivated meat research.

Icon cultivated Cultivated Commercial Ecosystem Research Compliance R&D Cell culture media Cell line development End product formulation & manufacturing
Developing open-access model production facility blueprints

Open-access blueprints would provide a head start on facility design and allow equipment manufacturers and engineering companies to address standard industry needs.

Icon cultivated Cultivated Icon fermentation Fermentation Icon plant based Plant-Based Commercial Research Production R&D Bioprocess design End product formulation & manufacturing 1 – Inception
Systematic investigation of growth factor needs and effects

Open-access research into growth factors required for proliferation, maintenance, and differentiation of cell types relevant to cultivated meat will support both academic and industry research efforts. This research could include…

Icon cultivated Cultivated Icon fermentation Fermentation Research R&D Raw Materials, Ingredients, & Inputs Cell culture media Target molecule selection

Get involved

If you’d like to fund a research project, work on any of these solutions, share information about related efforts that are already underway, or elevate new ideas for advancing the alternative protein industry, we’d love to hear from you!

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Explore key innovation priorities

Review commercial whitespaces, research gaps, technological needs, and investment priorities at each stage of the alternative protein value chain.

How we built this

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Executive summary

Get an overview of GFI’s Solutions initiative and a summary of key resources.

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Full report

Delve into the full report on the motivation, methodology, rationale, and key findings and recommendations of the Solutions initiative.

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Futures wheels analysis

Explore our framework for uncovering second-order or third-order consequences and implications of hypothetical future scenarios to support better decision-making in the present.

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Future-proofing

Discover key findings from GFI’s premortem analysis of potential threats to the widespread adoption of alternative proteins, including strategies to avoid or mitigate the most pressing risks.