Alternative Protein Solutions Database
Discover ideas for new startups, commercial ventures and products, research projects, ecosystem support, and investment opportunities for plant-based, cultivated, and fermentation-derived proteins.
|Opportunity||Production platform||Value chain segment||Technology sector||End product focus||Relevant actor||Maturity level||Solution category||Topic|
Promoting stemness and proliferation in fish cell cultures
Efficient and cost-effective cultivated fish production will require precise optimization to encourage fast proliferation and highly efficient use of inputs while preventing premature differentiation. A variety of strategies can be…
|Cultivated||Production R&D||Cell culture media Cell line development||Seafood||Academics Industry Startups||Research||Science|
Incorporating omega-3s into cultivated seafood
Cultivated seafood will need to be supplemented with long-chain omega-3 polyunsaturated fatty acids to be nutritionally equivalent or superior to conventional seafood. However, how these compounds can best be incorporated…
|Cultivated||Production R&D Raw Materials, Ingredients, & Inputs||Bioprocess design Cell culture media Cell line development End product formulation & manufacturing Scaffolding||Seafood||Academics Industry Startups||Commercial Research||Industry Science|
Cultivated meat makerspaces to promote public engagement
Both the cultivated meat industry and interested members of the general public would benefit from the creation of makerspaces focused on cultivated meat. These would be publicly available spaces where…
|Cultivated||R&D Workforce||Bioprocess design Cell culture media Cell line development Scaffolding||Species-agnostic||Academics Donors GFI Industry NGO’s Startups||Ecosystem Research||Science|
Co-cultured support cells for cultivated meat
Cultivated meat research focuses primarily on muscle fibers and fat cells. However, other cell types serve functions that are often under appreciated in their relevance to cultivated meat. Co-culture methods…
|Cultivated||Production R&D Raw Materials, Ingredients, & Inputs||Bioprocess design Cell culture media Cell line development||Seafood-relevant||Academics Industry Startups||Commercial Research||Science|
Metabolic modeling for cultivated meat
Academic researchers or consortia consisting of several cultivated meat companies should undertake research aimed at understanding metabolic pathways and fluxes within cultivated meat-relevant cell types. The outputs of this research…
|Cultivated||R&D||Bioprocess design Cell culture media Cell line development||Seafood-relevant||Academics Industry Investors Startups||Research||Science|
Understanding uptake and interconversion of omega-3 fatty acids by cultivated fish cells
Although fish are one of the best dietary sources of long-chain omega-3 fatty acids (FAs), these compounds are mostly bioaccumulated from a fish’s diet rather than synthesized de novo. Consistent…
|Cultivated||R&D Raw Materials, Ingredients, & Inputs||Cell culture media Cell line development Host strain development||Seafood||Academics Industry Startups||Commercial Research||Science|
Scaffolding development for culinary and biomechanical requirements of cultivated seafood
A number of published studies have focused on scaffolds for cultivated meat (see Related Efforts) yet, to our knowledge, no studies have specifically attempted to formulate scaffolds for fish or…
|Cultivated||R&D Raw Materials, Ingredients, & Inputs||Cell line development Scaffolding||Seafood||Academics Industry Startups||0 – Complete whitespace||Commercial Research||Science|
Improving efficiency and assessment of adaptation to suspension growth
Improving methods for adapting cells to suspension culture can facilitate cell line development and bioprocess design for cultivated meat.
|Cultivated||R&D||Bioprocess design Cell line development||Seafood-relevant||Academics Industry Startups||1 – Inception||Research||Industry Science|
Species-specific genomic studies enabling assay development for regulatory standards and cell line optimization
A suite of assays and genomic knowledge exists for humans and commonly used laboratory species such as mice or fruit flies. However, the same species-specific infrastructure does not exist equally…
|Cultivated||R&D||Cell line development||Seafood-relevant||Academics Industry||Research||Science|
Guidelines for cultivated meat starter cell selection
Improving our understanding of the relative advantages and disadvantages of different cell types for cultivated meat would enable companies to make these decisions more effectively with less duplicative effort.
|Cultivated||R&D Raw Materials, Ingredients, & Inputs||Cell line development||Seafood-relevant||Academics||1 – Inception||Research||Science|
If you’d like to fund a research project, work on any of these solutions, share information about related efforts that are already underway, or elevate new ideas for advancing the alternative protein industry, we’d love to hear from you!
Explore key innovation priorities
Review commercial whitespaces, research gaps, technological needs, and investment priorities at each stage of the alternative protein value chain.
How we built this
Get an overview of GFI’s Solutions initiative and a summary of key resources.
Delve into the full report on the motivation, methodology, rationale, and key findings and recommendations of the Solutions initiative.
Futures wheels analysis
Explore our framework for uncovering second-order or third-order consequences and implications of hypothetical future scenarios to support better decision-making in the present.
Discover key findings from GFI’s premortem analysis of potential threats to the widespread adoption of alternative proteins, including strategies to avoid or mitigate the most pressing risks.