40Research opportunities
44Commercial whitespaces
39Ecosystem support needs
Key: Cultivated icon Cultivated Fermentation icon Fermentation Plant-based icon Plant-Based
Opportunity Production platform Solution category Value chain segment Technology sector Maturity level
Improving efficiency and assessment of adaptation to suspension growth

Improving methods for adapting cells to suspension culture can facilitate cell line development and bioprocess design for cultivated meat.

Cultivated icon Cultivated Research R&D Bioprocess design Cell line development 1 – Inception
Species-specific genomic studies enabling assay development for regulatory standards and cell line optimization

A suite of assays and genomic knowledge exists for humans and commonly used laboratory species such as mice or fruit flies. However, the same species-specific infrastructure does not exist equally…

Cultivated icon Cultivated Research R&D Cell line development
Guidelines for cultivated meat starter cell selection

Improving our understanding of the relative advantages and disadvantages of different cell types for cultivated meat would enable companies to make these decisions more effectively with less duplicative effort.

Cultivated icon Cultivated Research R&D Raw Materials, Ingredients, & Inputs Cell line development 1 – Inception
Mapping the secretome of animal myoblasts, adipocytes, and other cells used in cultivated meat

Stem cells secrete a variety of signaling factors that can influence the behavior of surrounding cells, known as paracrine signals. In high-density bioprocesses, these secreted factors can accumulate to concentrations…

Cultivated icon Cultivated Research Production R&D Cell line development
Species-specific research toolkits for cultivated meat-relevant species

Coordinated efforts to develop standardized, comprehensive research toolkits of meat-relevant species would exponentially accelerate cultivated meat research.

Cultivated icon Cultivated Commercial Ecosystem Research Compliance R&D Cell culture media Cell line development End product formulation & manufacturing
Establishment of cell line repositories and standardized isolation protocols

Development of humanely-sourced and thoroughly documented and characterized cell lines from a variety of common food species—together with a mechanism for licensing and distributing these lines to researchers and companies—will…

Cultivated icon Cultivated Commercial Research R&D Raw Materials, Ingredients, & Inputs Cell line development
Developing assays for meat-specific cell traits

Research to align on the appropriate assays would introduce standardization that can accelerate R&D efforts.

Cultivated icon Cultivated Commercial Research Production R&D Cell line development
Understand animal and cellular efficiency, yield, and input

Because cultivated meat replicates the fundamental biology of the source animal, animal-level data may be informative for predicting cellular behavior in culture.

Cultivated icon Cultivated Research R&D Cell culture media Cell line development
Fat uptake & biosynthesis in cultivated meat cells

Determining which lipids muscle and fat cells are capable of producing and absorbing directly from cell culture media.

Cultivated icon Cultivated Research R&D Cell culture media Cell line development

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If you’d like to fund a research project, work on any of these solutions, share information about related efforts that are already underway, or elevate new ideas for advancing the alternative protein industry, we’d love to hear from you!

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Explore key innovation priorities

Review commercial whitespaces, research gaps, technological needs, and investment priorities at each stage of the alternative protein value chain.

How we built this

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Executive summary

Get an overview of GFI’s Solutions initiative and a summary of key resources.

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Full report

Delve into the full report on the motivation, methodology, rationale, and key findings and recommendations of the Solutions initiative.

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Futures wheels analysis

Explore our framework for uncovering second-order or third-order consequences and implications of hypothetical future scenarios to support better decision-making in the present.

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Future-proofing

Discover key findings from GFI’s premortem analysis of potential threats to the widespread adoption of alternative proteins, including strategies to avoid or mitigate the most pressing risks.