Host strain development

Solutions Database

Comprehensive microbial screening to identify new protein production candidate strains

Metabolic and physiological characteristics of microbial strains define the commercial potential of any fermentative process, but only a minimal number of strains have been scaled up for commercial production of alternative protein. To broaden the spectrum of available microorganisms, systematic investigation into the physiology of novel microbial strains is needed to identify strains suitable for fermentation.

1. 1 - Inception
2. Academics
3. Commercial
4. Fermentation
5. Host strain development
6. Industry
7. Industry
8. Production
9. R&D
10. Research
11. Science
12. Species-agnostic
13. Startups

Solutions Database

Producing animal-like fats through microbial fermentation

Microbial fermentation provides an efficient method for generating lipid molecules that are chemically identical to those produced by animals. Research efforts are needed to expand current knowledge about the process of engineering the appropriate metabolic pathways for the synthesis of animal lipids into microbial organisms well-suited for large-scale fermentation.

1. 1 - Inception
2. Academics
3. Commercial
4. Fermentation
5. Host strain development
6. R&D
7. Raw Materials, Ingredients, & Inputs
8. Research
9. Science
10. Species-agnostic
11. Startups
12. Target molecule selection

Solutions Database

Expanding options for food-safe genetic selection markers

In strain development, many of the selectable markers confer traits like antibiotic or herbicide resistance. While some auxotrophic selection markers exist, these are often not orthogonal and thus not amenable to stacking for multi-trait selection.

1. Academics
2. Fermentation
3. Host strain development
4. Industry
5. R&D
6. Research
7. Science
8. Species-agnostic
9. Startups

Solutions Database

Biosynthetic pathway discovery for fermentation-produced molecules

After identifying specific target molecules or desired functionalities in animal-derived foods, scientists can work backward, mining microbial sequences for candidate molecules in the microbial realm that might provide similar functionality. This process can also elucidate the pathways that produce these molecules and inform strategies for designing microbial strains that produce these molecules at scale.

1. Academics
2. Commercial
3. Fermentation
4. Host strain development
5. Industry
6. Industry
7. Ingredient optimization
8. Production
9. R&D
10. Raw Materials, Ingredients, & Inputs
11. Research
12. Science
13. Species-agnostic
14. Startups
15. Target molecule selection

Solutions Database

Fat production & encapsulation within oleaginous yeast

Oleaginous yeast can convert sugars into fats that impart flavor and mouthfeel to alternative proteins, and they can accumulate lipids within their cell bodies to inhibit oxidation. New research on lipid encapsulation in yeast should investigate the efficacy of yeast species for the accumulation and storage of lipids—including lipids with the same profile as animal lipids.

1. Academics
2. Commercial
3. Fermentation
4. Host strain development
5. Industry
6. Industry
7. Ingredient optimization
8. Production
9. R&D
10. Raw Materials, Ingredients, & Inputs
11. Research
12. Science
13. Species-agnostic
14. Startups
15. Target molecule selection

Solutions Database

Suppressing hyper-branching of filamentous fungi

Prolonging continuous cultivation of filamentous fungi by suppressing hyper-branching to improve texture and boost production efficiency.

1. Academics
2. Bioprocess design
3. Commercial
4. Fermentation
5. Host strain development
6. Industry
7. Production
8. R&D
9. Research
10. Science
11. Species-agnostic