Bioprocess design

Solutions Database

Post-harvest processes and end product characterization for cultivated meat

A number of cellular processes occurring after slaughter are known to affect the quality and sensory properties of conventional meat. Cultivated meat will offer unprecedented control over these parameters and therefore over the quality of the final product, but it is critical to understand exactly how post-harvest processes for cultivated meat can or should differ from post-slaughter processes in conventional meat. This research can enable subsequent innovations in bioprocess design, media formulation, cell line development, or harvesting techniques to confer consistently high levels of meat quality from cultivated meat processes.

Solutions Database

Cultivated meat co-product valorization

Animal cell metabolism within cultivators can produce useful co-product side streams that provide monetary value to the manufacturer while creating a novel source of inputs for other industries. Potential side streams should be identified and analyzed for their utility and economic viability, in addition to developing methods for efficient side stream capture.

Solutions Database

3D microenvironments for cell expansion

Proliferation and high-density cell growth are fundamentally important to scaling cultivated meat production. Recent demonstrations of stem cell expansion in 3D microenvironments such as encapsulated spheres or tubules can generate cell densities far higher than industry-leading stirred tank bioreactors with minimal loss of cell viability or stemness. As a scalable platform, the use of 3D microenvironments for stem cell expansion and differentiation—particularly with the relevant cell types used in cultivated meat—warrants further investigation.