Reducing cell culture media cost


Dr. Burridge is exploring a process to optimize chemically-defined media protocols around the generation, long-term culture, and scalable differentiation of non-genetically modified porcine and bovine induced pluripotent stem cells (iPSCs).


TECHNOLOGY SECTOR:  Cell culture media

Gfi's competitive research grants program badge, featuring a whole cut of meat within a magnifying glass representing research

Project aims

This project will work to develop low-cost induced pluripotent stem cell (iPSC) culture and differentiation media. The outcomes will help optimize protocols for bovine and porcine iPSC proliferation and differentiation. This work will also develop skeletal muscle maturation protocols to improve the organoleptic properties of these cells and adapt the differentiation protocol to larger bioreactors. As a result, it will improve the quality and reduce the costs of iPSC culture and differentiation media.

Principal researcher

Dr. Paul burridge, assistant professor, northwestern university, usa

Dr. Paul Burridge

Assistant professor, Northwestern University, USA

Dr. Burridge has experience developing differentiation protocols for biomedical research. His expertise is in using induced pluripotent stem cells (iPSCs) in pharmacogenomics (precision medicine), cardio-oncology, cardiovascular disease modeling, cultivated meat, regenerative medicine, and cancer.

Rendering of cell molecules

Commercialization of Dr. Burridge’s stem cell culture media

Dr. Burridge and an industry startup, Defined Bioscience, are actively working to commercialize a fully-defined, optimized culture medium for human stem cells. Given this, we are confident in Dr. Burridge and his Northwestern University lab’s ability to do the same for utilizing animal stem cells for cultivated meat.

Plant-based meat on a grill

Optimizing media for chicken cells

Learn about Dr. David Block’s work to perfect growth media for cultivated chicken at University of California, Davis.

An abstract field of white molecular models

Formulating media with macromolecular crowding

Learn about Dr. Connon and Dr. Gouveia’s work at Newcastle University, UK to formulate growth media for cultivated meat with macromolecular crowding.


Low-cost differentiation medium for seafood culture

Learn about Dr. Rees’s research to develop low-cost differentiation media for cultivated seafood at Defined Bioscience.

Explore research opportunities

  • Cultivated icon Cultivated
  • Fermentation icon Fermentation
  • Plant-based icon Plant-Based

Scientist / engineer outreach and education

To expand the technical talent pipeline, various players in the alternative protein field should reach out to scientists and engineers in relevant disciplines (e.g., biotech, biopharma, and food science) to…

Read More
  • Cultivated icon Cultivated

B2B media development company

The cultivated meat industry needs dedicated suppliers of low-cost, food-grade cell culture media to reduce cultivated meat production costs. Close collaboration between the customer and supplier will be required in…

Read More
  • Cultivated icon Cultivated
  • Fermentation icon Fermentation
  • Plant-based icon Plant-Based

Life Cycle Assessment for alternative seafood relative to conventional fishing and aquaculture

To date, no robust environmental assessments have been conducted to compare alternative seafood to its conventional counterparts. An open-access, quantitative analysis of the relative environmental impacts of alternative seafood will…

Read More

Clean meat production cover art

Analyzing cell culture medium costs

This white paper explains different routes to lowering the cost of cell culture medium and making cultivated meat economically viable.

Scholar holding molecular model, representing biomedical science concept

Translating biomedical advances to cultivated meat (Biochemical Engineering Journal)

This peer-reviewed article discusses how advances from the biomedical cell culture industry can contribute to the development of cultivated meat.

A battered and fried cultured meat, a cultured chicken cutlet, plated with sauteed greens and mashed root vegetables | image courtesy of upside foods

The science of cultivated meat

Learn about the science of cultivated meat and the challenges that must be addressed for commercial production.