Cultivated icon Cultivated

Uptake and biosynthesis of fat in cultivated meat cells

Determining which lipids muscle and fat cells are capable of producing and absorbing directly from cell culture media.

Production platform
  • Cultivated icon Cultivated
Solution category
  • Research
Value chain segment
  • R&D
Technology sector
  • Cell line development
  • Cell culture media
Relevant actor
  • Academics


While fat is widely acknowledged as a key contributor to the flavor of meat, it may not be straightforward to recapitulate meat’s fat profile in culture. In animals, many lipids are absorbed from the diet rather than synthesized, and lipid synthesis often occurs in other organs such as the liver for subsequent transport to fat tissue. Research is required to determine which lipids muscle and fat cells are actually capable of producing—and from which precursors—with high efficiency, and which lipids they are able to absorb directly from the cell culture media. This will be especially valuable for desirable fats like EPA and DHA in cultivated seafood.

GFI resources

Cultivated grilled chicken on a bed of mushroom pasta and herbs viewed from above

Cultivated meat

This is your guide to cultivated meat. Explore our tools, resources, and expert analysis of the cultivated meat industry.

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This professor is figuring out how to produce, scale, and combine muscle and fat for cell-based meat

Dr. Petra Hanga is working to optimize cell-based meat production by creating a robust and reliable scale-up process for fat and muscle cells.

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  • Fermentation icon Fermentation

Fat production & encapsulation within oleaginous yeast

Oleaginous yeast can convert sugars into fats that impart flavor and mouthfeel to alternative proteins, and they can accumulate lipids within their cell bodies to inhibit oxidation. New research on…

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  • Cultivated icon Cultivated

Understand animal and cellular efficiency, yield, and input

Because cultivated meat replicates the fundamental biology of the source animal, animal-level data may be informative for predicting cellular behavior in culture.

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  • Cultivated icon Cultivated

Mapping the secretome of animal myoblasts, adipocytes, and other cells used in cultivated meat

Stem cells secrete a variety of signaling factors that can influence the behavior of surrounding cells, known as paracrine signals. In high-density bioprocesses, these secreted factors can accumulate to concentrations…

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Browse 300+ startup ideas, commercial opportunities, research projects, and investment priorities throughout the alternative protein supply chain.

Golden oil droplets, representing fat encapsulation for plant-based meat

Fat encapsulation

Learn about Dr. Ricardo San Martin’s research incorporating oleogels into plant-based meat at University of California, Berkeley.

An abstract field of white molecular models

Formulating media with macromolecular crowding

Learn about Dr. Connon and Dr. Gouveia’s work at Newcastle University, UK to formulate growth media for cultivated meat with macromolecular crowding.

Plant-based meat on a grill

Optimizing media for chicken cells

Learn about Dr. David Block’s work to perfect growth media for cultivated chicken at University of California, Davis.

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