Biomanufacturing scaffold-free cultivated meat
Dr. Lei is working to develop a scaffold-free process to assemble and mature cell masses into meat.
PRODUCTION PLATFORM: Cultivated
TECHNOLOGY SECTOR: Bioprocess design
This project will work to translate scalable processes for high-volume tissue fabrication from the biomedical field to cultivated meat production. It will also develop a scaffold-free method for producing large volumes of thick cultivated meat. Ultimately, it will help develop a scalable platform technology to enable biomanufacturing of cultivated meat at large volumes and affordable prices.
Dr. Yuguo “Leo” Lei
Associate professor, Penn State University, USA
Dr. Lei has experience with large-scale cell biomanufacturing, mesenchymal stem cell therapy, cancer immunotherapies, and combinatorial biotherapeutics. His expertise is in developing next-generation cell culture and tissue fabrication technologies at various scales and costs. He is the faculty director of the Sartoris Mammalian Cell Culture Facility.
Learn about cutting-edge alternative protein research funded by GFI. Find funding opportunities for your own research.
View related grant projects
GFI grantees Dr. Ivana Gadjanski and Dr. Vasa Radonic are integrating sensors into bioreactors for cultivated meat production.
Learn about Dr. Iftach Nachman’s research to assemble skeletal muscle organoid building blocks into thick whole-cuts at Tel Aviv University.
Learn about Dr. Kelly Schultz’s research to develop hybrid scaffolds for cultivated meat structuring, nutrient sensing, and scaleup at Lehigh University.
Learn about Dr. Mohamadmahdi Samandari’s research to integrate intramuscular fat and textural fibers into cultivated meat at University of Connecticut.
Explore research opportunities
Consumer education on the food safety of cultivated meat can positively impact consumer acceptance when sufficient information is provided. Additional research and efforts to increase transparent science communication on the…
Sterilization guidelines from well-established biomedical and food industries can act as helpful templates for safe cultivated meat production. However, more research is needed to identify potentially novel production hazards for…
Growth factors (GFs) can be incorporated into scaffolds as a strategy for both reducing costs and improving product quality of cultivated meat. Open-access research is needed to test the feasibility…
Check out related resources
State of the Industry Report: Cultivated Meat
This global analysis of the cultivated meat industry covers investments, consumer insights, and scientific progress in this growing market sector.
Explore startup ideas, commercial opportunities, research projects, and investment priorities throughout the alternative protein supply chain.