Designing cost-effective bioreactors
2020-2021
Dr. Ellis is exploring the interplay between bioreactors, media, and scaffold designs to identify ways to reduce the cost of cultivated meat production.
PRODUCTION PLATFORM: Cultivated
TECHNOLOGY SECTOR: Bioprocess design

Project aims
This project aims to establish growth media consumption and waste production profiles for both proliferation and differentiation in various bioreactors. It will also produce correlations for the relationship among scaffold structure, fluid dynamics, and biological profiles in bioreactors.
This work will improve our understanding of how cell behavior changes as culture size increases, and could help develop a more compact, cost-effective bioreactor for cultivated meat production in novel scenarios.
Principal researcher

Dr. Marianne Ellis
Senior Lecturer, Associate Professor, University of Bath, UK
Dr. Ellis holds a strong academic and commercialization track record with expertise in tissue engineering and bioprocess design. She has published 30 reviews and articles on cellular agriculture, tissue engineering, and bioprocess design for a range of applications. She is also the founder of successful startup Cellesce Ltd., and co-founder of Cellular Agriculture Ltd.

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Research grants
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Co-culturing cells
GFI grantee Dr. Mariana Petronela Hanga is researching culturing different cell types at the same time.

Computational modeling
GFI grantee Dr. Simon Kahan at the Cultivated Meat Modeling Consortium is using computational modeling to improve bioreactor design for meat cultivation.
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