How to make amino acids more affordable for cultivated meat

Unlocking a cost-effective amino acid supply is essential to scaling the cultivated meat industry. Amino acids represent a significant cost driver for cultivated meat production, due not only to the large quantities required, but also the complex supply chain needed to deliver them at the scale and suitability for food applications. 

This novel study combines future amino acid requirements, alternative sourcing strategies, and real-world price data to help stakeholders across the value chain prioritize the most impactful research and supply chain solutions as the cultivated meat industry scales.

Key findings

  • The amino acid cost contribution to cultivated meat production could fall below $5/kg cultivated meat, representing a major improvement over previous estimates of approximately $18–$19/kg.
  • Hydrolysates from raw materials hold long-term promise as cost-effective alternatives to amino acid fermentation. But their uptake is limited by technical challenges.
    • The modeled price targets of $1.51–$11.27/kg for hydrolysates to compete with fermentation-derived amino acids are within reach. 
    • Batch-to-batch variability, solubility issues, and limited compositional data remain barriers to widespread adoption.
  • High cost and supply-constrained amino acids present new innovation and sourcing opportunities. 
    • Six amino acids — serine, glutamine, asparagine, histidine, proline, and arginine — pose high risks to scaling cultivated meat due to cost, limited supply, and difficulty replacing them with alternatives. 
    • Strategic efforts to improve production efficiency, diversify sourcing, and stabilize prices of these high-impact inputs will be critical for long-term scalability.

Data highlights

Bar chart showing the total amino acid cost contributions to a commercial media across four price scenarios, with a red reference line at $0. 20/l to represent recent reports from companies in the sector.

Figure 1. Total amino acid cost contributions to a commercial media across four price scenarios.

Heatmap showing high-risk amino acids from this analysis, defined as amino acids that are cost drivers, potential supply bottlenecks, and difficult to replace with hydrolysates.

Figure 2. Heatmap showing high-risk amino acids from this analysis.

Projected total amino acid requirements to produce 250 kta of cultivated meat, based on eight bioconversion efficiency estimates.

Figure 3. Projected total amino acid requirements to produce 250 kilotonnes of cultivated meat.

Shows four amino acid prices: feed-grade, low food-grade, high food-grade, and prices based on the humbird et al.  2021 study.

Figure 5. Amino acid price data (based on quotes and information obtained during interviews).

Stacked bar charts showing individual amino acids that contribute 10% or more of the total amino acid cost in media.  shows two media formulation scenarios.

Figure 7. Individual amino acid cost drivers in FSF4 and modified CHO media based on multiple pricing scenarios.

Estimated costs of amino acids per kg of cm across multiple bioconversion efficiencies and pricing scenarios.

Figure 9a. Estimated costs of amino acids per kg of CM across multiple bioconversion efficiencies and pricing scenarios.

Top raw material or hydrolysate blends for one of four blending scenarios.

Figure 11. Top raw material or hydrolysate blends for one of four blending scenarios.

Amino acid cost and supply chain analysis for cultivated meat webinar

Join the webinar

Experts Elliot Swartz and Marie Gibbons explore this novel analysis of amino acid scaling pathways for cultivated meat using real-world data and industry expertise. Learn how suppliers, CM producers, governments, and researchers can unlock the full potential of cultivated meat.

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Downloads available: 

  • Full technical report
  • Supporting data
  • Interactive models for production volume, cost, hydrolysate blend optimization, and hydrolysate price targets
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Citation and DOI information

Gibbons, M., A. Bess, and E. Swartz. Amino acid cost and supply chain analysis for cultivated meat. Washington D.C.: Good Food Institute. 2025. https://doi.org/10.62468/xcjx6040