Guidelines for cultivated meat starter cell selection
Improving our understanding of the relative advantages and disadvantages of different cell types for cultivated meat would enable companies to make these decisions more effectively with less duplicative effort.
- Raw Materials, Ingredients, & Inputs
- Cell line development
- 1 – Inception
Deciding which starting cell type to isolate and bank is a key process consideration for cultivated meat companies. Source material may include embryonic stem cells, induced pluripotent stem cells, mesenchymal stem cells, or adult muscle stem cells, and there appears to be little to no consensus at this stage in the cultivated meat field regarding which is preferable. Improving our understanding of the relative advantages and disadvantages of different cell types for each economically important species of cultivated meat in a systematic way would enable companies to make these decisions more effectively with less duplicative effort.
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Mapping the secretome of animal myoblasts, adipocytes, and other cells used in cultivated meat
Stem cells secrete a variety of signaling factors that can influence the behavior of surrounding cells, known as paracrine signals. In high-density bioprocesses, these secreted factors can accumulate to concentrations…
Establishment of cell line repositories and standardized isolation protocols
Development of humanely-sourced and thoroughly documented and characterized cell lines from a variety of common food species—together with a mechanism for licensing and distributing these lines to researchers and companies—will…
Open-access formulations & optimization methods for cell culture media and growth factor cocktails
The availability of more open-access formulations will provide a foundation to enable both academic researchers and startup companies to develop their own customized formulations with far less effort and cost.
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