Optimizing growth media for bovine cells
2024 – 2026
Dr. Betenbaugh is developing a model-based approach to optimize media to reduce the cost of cultivated meat and improve product yield and quality.
Production platform: Cultivated
Technology sector: Cell culture media, Computational modeling
Project aims
This project aims to create a computational model that simulates bovine cell cultivation and optimizes cell culture media by understanding their metabolic needs. Based on data from cell culture experiments, the model will be applied to limit the amount of nutrients in media while maximizing their growth, with the goal of reducing media costs. The model will also allow for the tailoring of biomass composition in cells through changes to media components.
This research will yield an efficient and tailorable model for optimization of cell culture media for cultivated meat. It will also establish a pipeline for the creation of similar models for various other cultivated meat cell types and species.
Principal researchers
Michael Betenbaugh
Professor, Department of Chemical and Biomolecular Engineering
Johns Hopkins University, United States
Dr. Betenbaugh has extensive experience in cell culture bioprocessing and metabolic engineering focused on improving bioproduction yields, quality, and efficiency.
Research Grant Program
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