Optimizing growth media for bovine cells

2024 – 2026

Dr. Betenbaugh is developing a model-based approach to optimize media to reduce the cost of cultivated meat and improve product yield and quality.

Production platform: Cultivated

Technology sector: Cell culture media, Computational modeling

Sci23066 cm

Project aims

This project aims to create a computational model that simulates bovine cell cultivation and optimizes cell culture media by understanding their metabolic needs. Based on data from cell culture experiments, the model will be applied to limit the amount of nutrients in media while maximizing their growth, with the goal of reducing media costs. The model will also allow for the tailoring of biomass composition in cells through changes to media components.

This research will yield an efficient and tailorable model for optimization of cell culture media for cultivated meat. It will also establish a pipeline for the creation of similar models for various other cultivated meat cell types and species.

Principal researchers

Sci24019 23 cm us fc 1 746 betenbaugh headshot

Michael Betenbaugh

Professor, Department of Chemical and Biomolecular Engineering

Johns Hopkins University, United States

Dr. Betenbaugh has extensive experience in cell culture bioprocessing and metabolic engineering focused on improving bioproduction yields, quality, and efficiency. 

Gfi's research grant program badge

Research Grant Program

Explore grant opportunities and GFI-funded projects that are driving innovation and breaking boundaries in alt protein research.