Low-cost differentiation medium for seafood
2021 – 2024
Dr. Rees, Dr. Ovissipour, and Dr. Duscher are working to develop robust, low-cost differentiation media for seafood culture.
Production platform: Cultivated
Technology sector: Cell culture media

Project aims
This project will help develop myogenic and adipogenic differentiation media for zebrafish (Danio rerio) embryonic stem cells (ESCs) and adapt this media for sea bass culture. This would reduce costs and optimize media formulations for cultivated seafood production. Beyond zebrafish and sea bass, this work will provide a strong foundation for the development of successful cultivation of other fish species and fish-like cell lines.
Principal Investigator

Dr. Steven Rees
CEO
Defined Bioscience, Inc., USA
Dr. Rees has a background in biomedical sciences with training in molecular biophysics, pharmacology, and multiscale biology. He is currently focused on creating high-quality reagents, media, and protocols that will reduce the cost of growing stem cells from humans and animals.
Additional researchers
- Dr. Reza Ovissipour, Assistant professor, Virginia Tech University, USA
- Dr. Lexi Duscher, Postdoctoral associate, Virginia Tech University, USA
Research Grant Program
Explore grant opportunities and GFI-funded projects that are driving innovation and breaking boundaries in alt protein research.