Genome-scale metabolic model of porcine cells

Project aims

The aim of this project is to develop a precise and robust proteome-constrained genome-scale metabolic model of porcine cells. This model will be refined and validated using -Omics experimental data obtained from time-course studies of the expansion and differentiation phases of pork cell lines provided by Meatable. Then, the model will enable us to understand why cell biology changes during proliferation and to design interventions that allow for longer expansion phases at faster population doublings, increasing yield and reducing process variability.