There are a number of factors that affect the yield of cultivated meat production in bioreactors, including mass transfer, mixing, hydrodynamic stress, and metabolite concentrations. In this work, computational workflows are being developed to efficiently predict the yield limits of each of these factors. One workflow builds on existing techno-economic analysis models by adding computational fluid dynamics and Bayesian optimization to provide predictions of optimum mass transfer, mixing, and hydrodynamic stress bioreactor performance. A second adds genome-scale metabolic modeling to predict cell growth response to metabolite concentrations. This presentation describes these workflows, detailing progress thus far and the need for further specific developments.
Meet the speaker
Dr. Simon Hubbard, MIMechE
LEAD ENGINEER AND OWNER, UPSTREAM APPLIED SCIENCE LTD.
Simon has been running his solo consulting business for almost four years, focusing primarily on the development and application of computational models in the cellular agriculture space. Prior to starting Upstream Applied Science, Simon spent time in the motorsport, high-tech product development, and technology consulting sectors. He has broad experience in computational simulation and mathematical modeling, with a focus on fluid dynamics simulation tools and applications.
Join GFI’s Adam Leman, Ph.D., for a free webinar discussing the opportunities and benefits of fermentation.
Join a GFI-hosted seminar with experts Emilie Fitch, AnnaMaria White, and Nico Westermann to learn about developing an effective marketing and communications strategy for your alternative protein startup.
Discover the food revolution and understand how innovation fuels the core of Culinology® transformation at the 2024 RCA Conference.
Several members of GFI’s Corporate Engagement Team will be attending and speaking at Expo West, one of the leading natural products trade shows.
Join us to explore academic and industry careers in alternative protein. Learn how you can apply your skills to this exciting and thriving field!
Discover the key scale-up and bioprocessing takeaways from a comprehensive survey of 30 cultivated meat companies and suppliers at our webinar on March 20th.
Join GFI’s roundtable at one of the leading alternative protein industry events.
The Novel Strain Engineering & Development for Alternative Proteins Summit in San Francisco, March 2024, will bring together a community of over 60+ industry leaders, including 18 world-class speakers who…